How Effective is Hand Sanitizer Against Germs and Viruses?

In today’s health-conscious world, hand sanitizers have become a staple in every handbag, home, and office. But just how effective are they against germs and viruses, and do they truly replace handwashing?

According to Cheryl Gan, Co-Founder of Hysses,

“Hand sanitizers are a convenient line of defence, especially when soap and water aren’t available. But not all sanitizers are made equal, their formulation and alcohol concentration directly affect their germ-fighting power.”

Let’s break down the science behind hand sanitisers, their effectiveness, limitations, and when to use them safely.

How Hand Sanitisers Work

Hand sanitisers are designed to kill or deactivate germs on contact mainly through alcohol-based formulas that denature proteins and dissolve lipids in bacteria and viruses.

According to the Centers for Disease Control and Prevention (CDC), sanitizers that contain at least 60% alcohol (either ethanol or isopropanol) are most effective in reducing the number of microbes on the skin.

At Hysses, our Tea Tree Hand Sanitiser Gel and Bergamot Hand Sanitiser Spray are formulated with 70% natural ethyl alcohol, combined with pure essential oils that not only disinfect but also protect and nourish the skin barrier, something most generic sanitisers overlook.

How Effective Are They Against Germs and Viruses?

Against Bacteria

Alcohol-based sanitizers are highly effective against common bacteria such as E. coli, Salmonella, and Staphylococcus aureus. These microbes have weaker lipid membranes, which alcohol quickly disrupts.

Against Viruses

Effectiveness varies by virus type:

• Enveloped viruses (like influenza, coronaviruses, and SARS-CoV-2) are vulnerable to alcohol-based sanitizers.

• Non-enveloped viruses (like norovirus and rotavirus) are more resistant, and require thorough handwashing with soap and water.

The Limitations of Hand Sanitisers

While sanitizers offer convenience, they do have boundaries:

• They cannot remove dirt, grease, or heavy organic matter.

• They are less effective when hands are visibly soiled.

• Overuse can dry out or irritate the skin, especially with synthetic formulations containing artificial fragrances or harsh chemicals.

To combat this, Hysses formulates its sanitizers with plant-based moisturisers and pure essential oils like lavender, tea tree, and bergamot, offering antimicrobial protection while maintaining the skin’s natural moisture balance.

When to Use Hand Sanitiser

Use a sanitizer when:

• You’re in public spaces (transport, offices, malls).
• After handling cash or shared objects.
• Before meals when soap and water aren’t available.
• After coughing, sneezing, or touching high-contact surfaces.

But whenever possible, wash your hands with soap and water for at least 20 seconds, especially after contact with bodily fluids, before eating, or after using the restroom.

Safer and More Sustainable Alternatives

Hysses encourages a holistic approach to hygiene, protecting yourself while being mindful of the planet.

Pair your sanitizing routine with:
Hysses Tea Tree Hand Sanitiser Gel - ideal for daily antibacterial protection.
Hysses Bergamot Hand Sanitiser Spray - refreshing and light, perfect for travel.
Hysses Lemongrass Hand Wash - gentle, natural cleansing with an invigorating scent.
Hysses Lavender Essential Oil - for natural antimicrobial and calming benefits.

By alternating between sanitizer and gentle handwashing, you ensure a complete, balanced hand-care regimen.

Frequently Asked Questions

1. Can I use hand sanitizer every day?
Yes. However, choose one with natural moisturisers and essential oils to prevent dryness and irritation.

2. Is non-alcohol sanitizer effective?
Non-alcohol sanitizers may reduce some germs but are generally less effective than those with at least 60% alcohol content.

3. Can sanitizer replace handwashing?
No, handwashing removes both germs and dirt. Sanitizer should complement, not replace, proper hygiene practices.

4. How much sanitizer should I use?
Use enough to cover all surfaces of your hands and rub until dry (about 20 seconds).

Final Thoughts

Hand sanitizers are an indispensable part of modern hygiene, offering quick protection in moments when soap and water aren’t accessible.

With Hysses’ natural essential oil-based sanitisers, you get the best of both worlds: effective germ defence and skin-loving care, crafted with the same purity and precision that defines every Hysses product.

References

• Centers for Disease Control and Prevention (CDC). “Show Me the Science – When & How to Use Hand Sanitizer.”

• World Health Organization (WHO). “Hand Hygiene in Healthcare Settings.”

• Gan, Cheryl. HYSSES Expert Commentary on Natural Hygiene and Essential Oils, 2025.